Big Joe McKinney— gambler, brawler, and life of the party— can solve any problem with his fists. Until he can’t. Chasing after the beautiful Rae, Joe’s bravado lands him and his two best friends on the front lines of a terrible war where they are captured and sentenced to be executed. Awaiting death, the friends begin to sing their favorite song- The St James Infirmary Blues. Unable to face the end or bare the weight of his responsibility, Joe cowers and can’t sing. When he’s knocked unconscious, Joe’s mind transports him into the world of the song— a fever dream where he must save Rae, mourn his friends, and face fate all while battling an evil doctor, confronting a vicious gambler, and fighting to keep everyone he loves out of St James.